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J60628 Ionomycin calcium salt, 99%

CAS Number
56092-82-1
Synonyms

Stock No. Size Price ($) Quantity Availability
J60628-#0 5mg 160.00
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Ionomycin calcium salt, 99%

MDL
MFCD00151183

Chemical Properties

Formula
C41H70CaO9
Formula Weight
747.08
Form
Crystalline powder
Storage & Sensitivity
Store at -20°C. Light Sensitive.
Solubility
Soluble in DMSO (10mg/ml). Also soluble in ethanol or methanol

Applications

Ionomycin calcium salt is used as a polyether antibiotic and apoptotic degeneration inducer. Ionomycin induces apoptotic degeneration of embryonic cortical neurons and cell cycle arrest at G1 phase. It is more effective than A23187 (sc-3591) and provides a useful tool for increasing intracellular Ca2+ concentration.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away fom strong oxidizing agents. Desiccate at 4°C

Literature References

Liu and Hermann. Characterization of ionomycin as a calcium ionophore. J.Biol.Chem.  1978, 253 ,(17 5892-4.

Elzi et al. Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils. Am.J.Physiol.Cell Physiol. 2001, 281 ,(1),, C350-60.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264b-P270-P301+P312-P330-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
1416163
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
NO0650000

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