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31282-04-9 - Hygromycin B - J60681 - Alfa Aesar

J60681 Hygromycin B

CAS Number
31282-04-9
Synonyms

Size Price ($) Quantity Availability
100mg 71.48
250mg 86.40
1g 129.78
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Hygromycin B

MDL
MFCD06795479
EINECS
250-545-5

Chemical Properties

Formula
C20H37N3O13
Formula Weight
527.53
Form
Lyophilized powder
Solubility
Miscible with water, methanol, buffer solution and ethanol. Immiscible with less polar solvents.

Applications

An aminoglycoside antibiotic that kills bacteria by inhibiting protein synthesisHygromycin B is used for the selection and maintenance of prokaryotic and eukaryotic cells that contains the hygromycin resistance gene. This gene is frequently used as a selectable marker in research on plants. It stabilizes the transfer ribonucleic acid (tRNA)-ribosomal acceptor site, thereby inhibiting translocation. In addition to this, it serves as an aminoglycosidic antibiotic which inhibits protein synthesis.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.Incompatible with strong oxidizing agents.

Literature References

Chen, C. F.; Chan, K. G.; Tan, B. C.; Khalid, N. Enhancement of Agrobacterium-mediated transformation efficiency of model plant using quorum sensing molecule, N-3-oxo-octanoyl-l-homoserine-lactone. Plant Cell Tissue Organ Cult. 2015, 121 (2), 481-487.

Park, Y.; Hosomichi, J.; Ge, C.; Xu, J.; Franceschi, R.; Kapila, S. Immortalization and characterization of mouse temporomandibular joint disc cell clones with capacity for multi-lineage differentiation. Osteoarthr. Cartil. 2015, 23 (9), 1532-1542.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H310-H330-H317-H334-H318

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes serious eye damage.

Precautionary Statements: P260-P284-P301+P310-P304+P340-P305+P351+P338-P320-P330-P361-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,4852
Hazard Class
6.1
Packing Group
I
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
WK2130000

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