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1070-11-7 - Ethambutol dihydrochloride - 2,2'-(1,2-Ethanediyldiimino)bis-1-butanol dihydrochloride - J60695 - Alfa Aesar

J60695 Ethambutol dihydrochloride

CAS Number
1070-11-7
Synonyms
2,2'-(1,2-Ethanediyldiimino)bis-1-butanol dihydrochloride

Size Price ($) Quantity Availability
5g 27.81
25g 129.78
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Ethambutol dihydrochloride

MDL
MFCD00216025
EINECS
213-970-7

Chemical Properties

Formula
C10H24N2O2•2HCl
Formula Weight
277.23
Form
Powder
Solubility
Slightly soluble in water

Applications

Ethambutol dihydrochloride it acts as a tuberculostatic antibacterial agent. It is used to treat tuberculosis in combination with other antibiotics to reduce the development of drug resistance. It has been used to study multidrug-resistant tuberculosis (MDR-TB) in highest-incidence-rate.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Literature References

Byeong-Ho Jeong et. al. Intermittent Antibiotic Therapy for Nodular Bronchiectatic Mycobacterium avium Complex Lung Disease. American Journal of Respiratory and Critical Care Medicine. 2015, 191,(1), 96-103.

K H Khoo et. Al. Truncated structural variants of lipoarabinomannan in ethambutol drug-resistant strains of Mycobacterium smegmatis. Inhibition of arabinan biosynthesis by ethambutol. Journal of Biological Chemistry. 1996, 271,(45), 28682-28690.

GHS Hazard and Precautionary Statements

Hazard Statements: H360

May damage fertility or the unborn child.

Precautionary Statements: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3720
Harmonized Tariff Code
2922.19
TSCA
No
RTECS
EL3854000

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