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J60705 Aminophylline, anhydrous, 98%

CAS Number
317-34-0
Synonyms
3,7-Dihydro-1,3-dimethylpurine-2,6-dione, complex with 1,2-ethanediamine (2:1)
Theophylline hemi(ethylenediamine) complex

Stock No. Size Price ($) Quantity Availability
J60705-14 25g 29.30
J60705-22 100g 81.70
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Aminophylline, anhydrous, 98%

MDL
MFCD00013221
EINECS
206-264-5

Chemical Properties

Formula
C7H8N4O2•0.5C2H8N2
Formula Weight
210.21
Form
Powder
Melting point
269-274°
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in water. Insoluble in alcohol and ether.

Applications

Aminophylline exhibits vasodilatory and anti-inflammatory activity and is occasionally clinically used to treat chronic obstructive pulmonary disorder (COPD). In animal models of allergen-induced lung inflammation, aminophylline decreases levels of IL-5, IL-8, and eosinophils. It is mostly used to prepare solutions for intravenous injections.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away fom strong oxidizing agents.

Literature References

L Hendele.; M Weinberger. Disposition of Theophylline after a Single Intravenous Infusion of Aminophylline 1-4. American Review of Respiratory Disease. 1978, 118,(1), 97-103.

JA Elias.; AI Levinson. Hypersensitivity Reactions to Ethylenediamine In Aminophylline 1-3. American Review of Respiratory Disease. 1981, 123,(5), 550-552.

GHS Hazard and Precautionary Statements

Hazard Statements: H301

Toxic if swallowed.

Precautionary Statements: P264b-P270-P301+P310-P330-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. Rinse mouth. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,465
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2939.59
TSCA
Yes
RTECS
XH5600000

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