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Enalapril is used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. It has been proven to protect the function of the kidneys in hypertension, heart failure, and diabetes, and may be used in the absence of hypertension for its kidney protective effects. It is widely used in chronic kidney failure.
CONSENSUS Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure : Results of the Cooperative North Scandinavian Enalapril Survival Study. N Engl J Med . 1987, 316 1429-1435.
S. Yusuf, FRCP,;, C.J. Pepine, MD,; C. Garces, MSc,; H. Pouleur, MD,; M. Rousseau, MD,; D. Salem, MD,; J. Kostis, MD,; C. Benedict, MD,; M. Bourassa, MD. Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions . Journal name. 1992, 340, ( 8829), 1173-1178.