J60793 CGS 21680 hydrochloride, 99%
SDS
| Stock No. | Size | Price ($) | Quantity | Availability |
|---|---|---|---|---|
| J60793-#0 | 5mg | 214.00 |
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| J60793-MA | 10mg | 337.00 |
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| J60793-MF | 50mg | 1460.00 |
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CGS 21680 hydrochloride, 99%
Chemical Properties
Applications
CGS 21680 hydrochloride is currently used in research in studying neuronal transmission, also in respiration. CGS 21680 is commonly used to study the actions of the adenosine A2A receptor in cells and tissues. CGS 21680 HCl is an adenosine A2 receptor agonist with IC50 of 22 nM, exhibits 140-fold over A1 receptor. CGS 21680C effectively increases coronary flow with an ED25 value of 1.8 nM. In hippocampal slices, CGS 21680 apis weak agonist on pre- and postsynaptic measures of electrophysiologicaJ activity.
Notes
Literature References
Cheng, M.K.,; Doumad, A.B., Jiang, H., et al. . Epoxyeicosatrienoic acids mediate adenosine-induced vasodilation in rat prelomerular microvessels (PGMV) via A2A receptors. . Br J Pharmacol . 2004, 141 441-448 .
Phillis,J.W.. The selective adenosine A2 receptor agonist, CGS 21680, is a potent depressant of cerebral cortical neuronal activity.. Brain Res.. 1990 , 509 328-330.
Other References
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