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1257-08-5 - (-)-Epicatechin gallate - (-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate - ECG - J60814 - Alfa Aesar

J60814 (-)-Epicatechin gallate

CAS Number
1257-08-5
Synonyms
(-)-cis-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol 3-gallate
ECG

Size Price ($) Quantity Availability
10mg 154.00
20mg 283.00
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(-)-Epicatechin gallate

MDL
MFCD00075936

Chemical Properties

Formula
C22H18O10
Formula Weight
442.37
Form
Powder
Solubility
Soluble in water, acetone, DMSO, methanol.

Applications

(-)-Epicatechin gallate is used as an antioxidant investigated as an adjunct treatment of some methyicillin resistant bacteria. Epicatechin gallate binds to the cell membrane in methicillin-resistant Staphylococcus aureus which decreases the fluidity of the bilayer and induces changes in gene expression. One of the catechin isomers and a potent antioxidant that can modulate a wide range of membrane proteins. Its bilayer-modifying potency was tested using gramicidin A (gA) channels as probes. All the catechins alter gA channel function and modify bilayer properties, with a 500-fold range in potency.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C

Literature References

SJ Baek.; JS Kim.; FR Jackson.; TE Eling. Epicatechin gallate-induced expression of NAG-1 is associated with growth inhibition and apoptosis in colon cancer cells. Carcinogenesis . 2015, 25,(12), S254-S296.

CT Ho.; Q Chen.; H Shi.; KQ Zhang.; RT Rosen. Antioxidative effect of polyphenol extract prepared from various Chinese teas. Preventive medicine . 1992, 21,(4), 520-525.

Other References

Harmonized Tariff Code
2932.99
TSCA
No
RTECS
DH9030000

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