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J60820 Bleomycin sulfate, mixture of salts

CAS Number
9041-93-4
Synonyms

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Bulk/Specialty

Bleomycin sulfate, mixture of salts

MDL
MFCD0070310
EINECS
232-925-2

Chemical Properties

Form
Powder
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water or DMSO

Applications

Bleomycin sulfate is used as a glycopeptide antibiotic. It is capable of inducing oxidative cleavage of the DNA backbone, leading to apoptosis and also degrades RNA, and has been reported to display selectivity for RNA over DNA. Bleomycin acts as a sclerosing agent.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Strongly Hygroscopic. Keep away fom strong oxidizing agents.

Literature References

WB Shelley.; ED Shelley. Intralesional bleomycin sulfate therapy for warts: a novel bifurcated needle puncture technique. Arch Dermatol. 1991, 127,(2), 234-236.

M Amer.; N Diab.; A Ramadan.; A Galal. Therapeutic evaluation for intralesional injection of bleomycin sulfate in 143 resistant warts. Journal of the American Academy of Dermatology. 2015, 73,(4), 533-720.

GHS Hazard and Precautionary Statements

Hazard Statements: H340-H351-H361d

May cause genetic defects. Suspected of causing cancer. Suspected of damaging the unborn child.

Precautionary Statements: P201-P202-P281-P308+P313-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use personal protective equipment as required. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,1318
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
EC5991990

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