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7220-79-3 - Methylene Blue trihydrate - C.I. 52015 - Basic Blue 9 - J60823 - Alfa Aesar

J60823 Methylene Blue trihydrate

CAS Number
7220-79-3
Synonyms
C.I. 52015
Basic Blue 9

Size Price ($) Quantity Availability
25g 22.90
100g 45.80
250g 91.70
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Methylene Blue trihydrate

MDL
MFCD00150008
EINECS
200-515-2

Chemical Properties

Formula
C16H18ClN3S•3H2O
Formula Weight
373.90 (319.86anhy)
Form
Green crystalline Powder
Solubility
Soluble in water, alcohol and chloroform. Insoluble in ether.

Applications

Methylene Blue trihydrate finds many uses in biology and chemistry. It acts as a GCS inhibitor, biological stain and redox indicator. It inhibits tau filament formation. Further, it is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes and thus exhibit antimuscarinic effects on IK, ACh and ICa. It also inhibits endothelium-dependent relaxation of isolated blood vessels.

Notes

Incompatible with strong oxidizing agents.

Literature References

Xu, P.; Wang, J.; Xu, Y.; Chu, H.; Shen, H.; Zhang, D.; Zhao, M.; Liu, J.; Li, G. Binding Modes and Interaction Mechanism Between Different Base Pairs and Methylene Blue Trihydrate: A Quantum Mechanics Study. Adv. Struct. Bioinform. 2015, 827, 187-203.

Chan, C. H.; Chia, C. H.; Zakaria, S.; Sajab, M. S.; Chin, S. X. Cellulose nanofibrils: a rapid adsorbent for the removal of methylene blue. RSC Adv. 2015, 5 (24), 18204-18212.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6060
Beilstein
3599847
Harmonized Tariff Code
3204.13
TSCA
Yes
RTECS
SP5740000

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