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Miconazole, is used as an antifungal inhibitor of aromatase. Miconazole has been shown to promote remyelination of neurons in chronic progressive multiple sclerosis mouse models. Miconazole is mainly used externally for the treatment of athlete's foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis. It is also used in photography.
White TC.; Marr KA.; Bowden RA. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev. 1998, 11,(2), 382-402.
Ghannoum MA.; Rice LB. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin Microbiol Rev. 1999, 12,(4), 501-17.
Hazard Statements: H302-H317
Harmful if swallowed. May cause an allergic skin reaction.
Precautionary Statements: P261-P280g-P301+P312a-P363-P321-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. IF SWALLOWED: Wash contaminated clothing before reuse. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.