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22916-47-8 - Miconazole, 99% - J60872 - Alfa Aesar

J60872 Miconazole, 99%

CAS Number
22916-47-8
Synonyms

Size Price ($) Quantity Availability
1g 15.30
5g 42.20
25g 163.00
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Miconazole, 99%

MDL
MFCD00216019
EINECS
245-324-5

Chemical Properties

Formula
C18H14Cl4N2O
Formula Weight
416.13
Form
Powder
Melting point
83-97°
Sensitivity
Light Sensitive
Solubility
Freely soluble in alcohols or acetone. Also soluble in DMF or chloroform. Insoluble in water

Applications

Miconazole, is used as an antifungal inhibitor of aromatase. Miconazole has been shown to promote remyelination of neurons in chronic progressive multiple sclerosis mouse models. Miconazole is mainly used externally for the treatment of athlete's foot, ringworm, and jock itch. Internal application is used for oral or vaginal thrush (yeast infection). The oral gel may also be used for the lip disorder angular cheilitis. It is also used in photography.

Notes

Protect from light. Store in well-closed containers.

Literature References

White TC.; Marr KA.; Bowden RA. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clin Microbiol Rev. 1998, 11,(2), 382-402.

Ghannoum MA.; Rice LB. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin Microbiol Rev. 1999, 12,(4), 501-17.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H317

Harmful if swallowed. May cause an allergic skin reaction.

Precautionary Statements: P261-P280g-P301+P312a-P363-P321-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6178
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
NI4770000

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