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60-92-4 - Adenosine-3',5'-cyclic monophosphate, 98% - 3',5'-Cyclic AMP - Adenosine 3',5'-cyclophosphate - J60936 - Alfa Aesar

J60936 Adenosine-3',5'-cyclic monophosphate, 98%

CAS Number
60-92-4
Synonyms
3',5'-Cyclic AMP
Adenosine 3',5'-cyclophosphate

Size Price ($) Quantity Availability
1g 111.00
5g 220.00
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Adenosine-3',5'-cyclic monophosphate, 98%

MDL
MFCD00005845
EINECS
200-492-9

Chemical Properties

Formula
C10H12N5O6P
Formula Weight
329.21
Form
Crystalline powder
Melting point
260° dec.
Solubility
Solube in water: 10 mg/mL pH of aqueous solution is approx. 3.0.

Applications

cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3?: 5?-cyclic monophosphate. In the presence of adenosine 3?:5?-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3?:5?-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3?,5?-cyclic monophosphate.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

Literature References

Alfred G. Gilman. A Protein Binding Assay for Adenosine 3?:5?-Cyclic Monophosphate. PNAS. 1970, 67 (1) , 305-312.

B L Brown,; J D Albano,; R P Ekins,; A M Sgherzi. A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate. Biochem J. . 1971, 121 (3), 561-562..

Other References

Merck
14,2708
Beilstein
52645
Harmonized Tariff Code
2934.99
TSCA
Yes
RTECS
AU7357600

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