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145-73-3 - Endothall - 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid - J60948 - Alfa Aesar

J60948 Endothall

CAS Number
145-73-3
Synonyms
7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Size Price ($) Quantity Availability
100mg 332.00
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Endothall

MDL
MFCD00137362
EINECS
205-660-5

Chemical Properties

Formula
C8H10O5
Formula Weight
186.20
Form
Powder
Solubility
Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.

Applications

Endothall is used as an inhibitor of PP2A phosphatase activity. It is also used as a defoliant. It is used as a cell adhesion inhibitor.

Notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

Literature References

F Erdodi.; B Toth.; K Hirano.; M Hirano. Endothall thioanhydride inhibits protein phosphatases-1 and-2A in vivo. American Journal of Physiology - Cell Physiology. 1995, 269 ,(5), C1176-C1184.

YM Li.; C Mackintosh.; JE Casida. Protein phosphatase 2A and its [3 H] cantharidin/[3 H] endothall thioanhydride binding site: Inhibitor specificity of cantharidin and ATP analogues. Biochemical pharmacology. 1993, 46 ,(8), 1435-1443.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H312-H315-H319-H335

Toxic if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3575
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
RN7875000

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