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J60948 Endothall

CAS Number
145-73-3
Synonyms
7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Stock No. Size Price ($) Quantity Availability
J60948-MC 100mg 309.00
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Endothall

MDL
MFCD00137362
EINECS
205-660-5

Chemical Properties

Formula
C8H10O5
Formula Weight
186.20
Form
Powder
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in water (>25 mg/ml), methanol, acetone, and DMSO. Insoluble in benzene.

Applications

Endothall is used as an inhibitor of PP2A phosphatase activity. It is also used as a defoliant. It is used as a cell adhesion inhibitor.

Notes

Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 12 months.

Literature References

F Erdodi.; B Toth.; K Hirano.; M Hirano. Endothall thioanhydride inhibits protein phosphatases-1 and-2A in vivo. American Journal of Physiology - Cell Physiology. 1995, 269 ,(5), C1176-C1184.

YM Li.; C Mackintosh.; JE Casida. Protein phosphatase 2A and its [3 H] cantharidin/[3 H] endothall thioanhydride binding site: Inhibitor specificity of cantharidin and ATP analogues. Biochemical pharmacology. 1993, 46 ,(8), 1435-1443.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H312-H315-H319-H335

Toxic if swallowed. Harmful in contact with skin. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P270-P271-P280-P301+P310-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,3575
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2932.99
TSCA
No
RTECS
RN7875000

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