1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.
Frija, L. M. T A.; Ismael, A.; Cristiano, M. L. S. Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis. Molecules 2010, 15 (5), 3757-3774.
Dabbagh, A. H.; Mansoori, Y. New azoic dyes containing (1H)-tetrazole and azido group. Dyes Pigm. 2002, 54 (1), 37-46.
Hazard Statements: H225-H303-H312-H332-H319
Highly flammable liquid and vapour. May be harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes serious eye irritation.
Precautionary Statements: P210-P261-P280-P303+P361+P353-P305+P351+P338-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Dispose of contents/container in accordance with local/regional/national/international regulations.