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72509-76-3 - Felodipine - Plendil - 3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate - J61195 - Alfa Aesar

J61195 Felodipine

CAS Number
72509-76-3
Synonyms
Plendil
3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

Size Price ($) Quantity Availability
50mg 130.00
100mg 208.00
250mg 386.00
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Felodipine

MDL
MFCD00868316

Chemical Properties

Formula
C18H19Cl2NO4
Formula Weight
384.25
Form
Crystalline powder
Solubility
Soluble in DMSO. Insoluble in water

Applications

Felodipine is used as a dihydropyridine calcium channel blocker. It displays high vascular selectivity; lowers arterial blood pressure without altering cardiac contractility. Antihypertensive.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.

Literature References

Ljung. Vascular selectivity of felodipine: experimental pharmacology. J.Cardiovasc.Pharmacol. 1990, 15,(4), S11-6.

Furukawa et al. Selectivities of dihydropyridine derivatives in blocking Ca2+ channel subtypes expressed inXenopus oocytes. J.Pharmacol.Exp.Ther. 1999, 291,(2), 464-73.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312a-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3953
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US7968700

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