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1263094-00-3 - 7-Chlorokynurenic acid sodium salt, 98% - J61283 - Alfa Aesar

J61283 7-Chlorokynurenic acid sodium salt, 98%

CAS Number
1263094-00-3
Synonyms

Size Price ($) Quantity Availability
10mg 72.71
50mg 360.00
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7-Chlorokynurenic acid sodium salt, 98%

MDL
MFCD12195840

Chemical Properties

Formula
C10H5ClNNaO3
Formula Weight
245.60
Form
Powder
Solubility
Soluble in water at 100mM

Applications

7-Chlorokynurenic acid sodium salt is used as a Potent competitive inhibitor of L-glutamate transport into synaptic vesicles. It is also used as an NMDA receptor antagonist and inhibitor of EAAT.

Notes

Store at room temperature (desiccating conditions). May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Literature References

Kretschmer et al. Behavioral and neurochemical actions of the strychnine-insensitive glycine receptor antagonist, 7-chlorokynurenate, in rats. Eur.J.Pharmacol. . 1995, 280, (1), 37-45.

Bartlett et al. Substituted quinolines as inhibitors of L-glutamate transport into synaptic vesicles. Neuropharmacology. 1998, 37, (7), 839-46.

Other References

Harmonized Tariff Code
2933.49
TSCA
No

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