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29270-56-2 - 4-Fluoro-7-nitrobenzofurazan - NBD-F - 4-Fluoro-7-nitro-2,1,3-benzoxadiazole - J61336 - Alfa Aesar

J61336 4-Fluoro-7-nitrobenzofurazan

CAS Number
29270-56-2
Synonyms
NBD-F
4-Fluoro-7-nitro-2,1,3-benzoxadiazole

Size Price ($) Quantity Availability
100mg 276.04
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4-Fluoro-7-nitrobenzofurazan

MDL
MFCD00010196

Chemical Properties

Formula
C6H2FN3O3
Formula Weight
183.10
Form
Powder
Melting point
53-57°
Flash Point
110°(230°F)
Solubility
It is soluble in DMSO, DMF, CH3OH, CH3CN and CHCl3.

Applications

4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of functionalized hydroxynaphthofurazan, Spectrophotometric and spectrofluorometric determination of clemastine hydrogen fumarate, loratadine, losartan potassium and ramipril in pharmaceutical formulations. Synthesis of 7-nitrobenzofurazan (NBD)-labeled maleimide, via Diels-Alder reaction. NBD-Cl is widely used to label peptides, proteins, drugs and other biomolecules. It is also a popular derivatizing reagent for HPLC analysis

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C Store under inert gas. Moisture sensitive. Keep away from strong bases.

Literature References

P.A.T. Martins et. al. Binding of phospholipids to β-Lactoglobulin and their transfer to lipid bilayers. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2008, 1778, (5), 1308-1315 .

El-Hay Soad S Abd et. Al. Utility of 4-chloro-7-nitrobenzofurazan (NBD-CI) for the Spectrophotometric and spectrofluorometric determination of several antihistamine and antihypertensive drugs. Journal of AOAC International. 2013, 96, (5), 968-975 .

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319

Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P280-P264-P305+P351+P338-P362-P321-P332+P313-P337+P313-P302+P352

Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Take off contaminated clothing and wash before reuse. Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. If eye irritation persists: IF ON SKIN: Wash with plenty of soap and water.

Other References

Beilstein
1077571
Harmonized Tariff Code
2934.99
TSCA
No

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