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6132-04-3 - Citrate, 0.5M buffer soln., pH 3.0 - J61391 - Alfa Aesar

J61391 Citrate, 0.5M buffer soln., pH 3.0

CAS Number

Size Price ($) Quantity Availability
250ml 56.24
500ml 88.37
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Citrate, 0.5M buffer soln., pH 3.0


Chemical Properties

Fully miscible in water. Insoluble in ethanol.


Citrate is an intermediate in the TCA cycle and fatty acid synthesis. It is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA. It has anticoagulant activity and is a calcium chelator. Its function is to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies.


Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.

Literature References

J.Steigman; G.Meinken; P.Richards. The reduction of pertechnetate-99 by stannous chloride—I. The stoichiometry of the reaction in HCl, in a citrate buffer and in a DTPA buffer. The International Journal of Applied Radiation and Isotopes. 1975, 26,(10), 601-609.


M.Seruga; M.Metikos-Hukovic; T.Valla; M.Milun; H.Hoffschultz; K.Wandelt. Electrochemical and X-ray photoelectron spectroscopy studies of passive film on tin in citrate buffer solution. Journal of Electroanalytical Chemistry. 1996, 407,(1-2), 83-89.

GHS Hazard and Precautionary Statements

Hazard Statements: H318

Causes serious eye damage.

Precautionary Statements: P280-P305+P351+P338-P310

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.

Other References

Harmonized Tariff Code


  • J63950

    Citrate, 0.5M buffer soln., pH 6.0
  • 33333

    Magnesium carbonate hydroxide tetrahydrate, Reagent Grade, MgO ≈40-43.5%

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