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56001-37-7 - Guanosine-5'-triphosphate disodium salt - GTP - J61414 - Alfa Aesar

J61414 Guanosine-5'-triphosphate disodium salt

CAS Number
56001-37-7
Synonyms
GTP

Size Price ($) Quantity Availability
250mg 255.44
500mg 392.00
1g 577.60
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Guanosine-5'-triphosphate disodium salt

MDL
MFCD00083629
EINECS
259-940-7

Chemical Properties

Formula
C10H14N5Na2O14P3
Formula Weight
567.15
Form
Powder
Solubility
Soluble in water.

Applications

Guanosine 5?-triphosphate (GTP), a purine trinucleotide, is a substrate for RNA polymerases and a wide range of GTPase including G-protein coupled receptor (GPCR) GTPases and cell signaling and cycling associated guanine nucleotide exhange factors (GEF). Guanosine 5?-Triphosphate, Disodium Salt is a phosphoryl donor in protein synthesis and in signal transduction.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agents.

Literature References

ES Simon.; S Grabowski. Convenient Syntheses of Cytidine 5'-triphosphate, Guanosine 5'-triphosphate, and Uridine 5'-triphosphate and their Use in the Preparation of UDP-Glucose, UDP. J. Org. Chem. 1990, 55, (6), 1834-1841.< p>

KE Achyuthan.; CS Greenberg. Identification of a guanosine triphosphate-binding site on guinea pig liver transglutaminase. Role of GTP and calcium ions in modulating activity. J.Biol.Chem. 1987, 262, 1901-1906.< p>

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
4113439
Harmonized Tariff Code
2934.99
TSCA
No

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