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1405-10-3 - Neomycin sulfate hydrate - J61499 - Alfa Aesar

J61499 Neomycin sulfate hydrate

CAS Number
1405-10-3
Synonyms

Size Price ($) Quantity Availability
25g 33.37
100g 104.03
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Neomycin sulfate hydrate

MDL
MFCD00150827
EINECS
215-773-1

Chemical Properties

Formula
C23H46N6O13•3H2SO4•xH2O
Formula Weight
908.87(anhy)
Form
Powder
Solubility
Soluble in water

Applications

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Nandi Zhou.; Jingyuan Wang.; Juan Zhang.; Can Li.; Yaping Tian.; Joseph Wang. Selection and identification of streptomycin-specific single-stranded DNA aptamers and the application in the detection of streptomycin in honey. Talanta. 2013, 108 109-116.

Xiaojing Bai.; Hui Hou.; Bailin Zhang.; Jilin Tang. Label-free detection of kanamycin using aptamer-based cantilever array sensor. Biosensors and Bioelectronics. 2014, 56, 112-116.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H317

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Precautionary Statements: P285-P261-P280-P342+P311-P363-P304+P341-P321-P333+P313-P302+P352-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment (see label). If skin irritation or rash occurs: Get medical advice/attention. IF ON SKIN: Wash with plenty of soap and water. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6454
Harmonized Tariff Code
2941.90
TSCA
Yes

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