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J61499 Neomycin sulfate hydrate

CAS Number
1405-10-3
Synonyms

Stock No. Size Price ($) Quantity Availability
J61499-14 25g 35.00
J61499-22 100g 107.00
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Neomycin sulfate hydrate

MDL
MFCD00150827
EINECS
215-773-1

Chemical Properties

Formula
C23H46N6O13•3H2SO4•xH2O
Formula Weight
908.87(anhy)
Form
Powder
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water

Applications

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria. Neomycin sulfate inhibits Phospholipase C via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNase I induced DNA degradation.

Notes

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

Literature References

Nandi Zhou.; Jingyuan Wang.; Juan Zhang.; Can Li.; Yaping Tian.; Joseph Wang. Selection and identification of streptomycin-specific single-stranded DNA aptamers and the application in the detection of streptomycin in honey. Talanta. 2013, 108 109-116.

Xiaojing Bai.; Hui Hou.; Bailin Zhang.; Jilin Tang. Label-free detection of kanamycin using aptamer-based cantilever array sensor. Biosensors and Bioelectronics. 2014, 56, 112-116.

GHS Hazard and Precautionary Statements

Hazard Statements: H317-H334-H361d-H373

May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Suspected of damaging the unborn child. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P201-P202-P260-P272-P280g-P281-P285-P302+P352-P304+P341-P308+P313-P333+P313-P342+P311-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not breathe dust/fume/gas/mist/vapours/spray. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves. Use personal protective equipment as required. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: If breathing is difficult, remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. If skin irritation or rash occurs: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,6454
Harmonized Tariff Code
2941.90
TSCA
Yes

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