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J61536 O-Acetyl-L-carnitine hydrochloride

CAS Number
5080-50-2
Synonyms
(R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride
L-Carnitine acetyl ester hydrochloride

Stock No. Size Price ($) Quantity Availability
J61536-06 5g 83.70
J61536-14 25g 282.00
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O-Acetyl-L-carnitine hydrochloride

MDL
MFCD00082230

Chemical Properties

Formula
C9H17NO4•HCl
Formula Weight
239.70
Form
White crystalline powder
Storage & Sensitivity
Keep Cold. Hygroscopic.
Solubility
Soluble in water (100 mg/ml), alcohol, and ethanol (10%). Insoluble in ether.

Applications

O-Acetyl-L-carnitine hydrochloride is used as a cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Hygroscopic. Keep away from strong oxidizing agents.

Literature References

Stieger, B.; O'Neill, B.; Krähenbühl, S. Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles. Biochem J . 1995, 309, ( Pt 2), 643-647.

Fu, L.; Huang, M.; and Chen.; S. Primary carnitine deficiency and cardiomyopathy. Korean Circ J. 2013, 43, ( 12), 785-792.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,84
Beilstein
4340103
Harmonized Tariff Code
2922.49
TSCA
No

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