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5080-50-2 - O-Acetyl-L-carnitine hydrochloride - (R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride - L-Carnitine acetyl ester hydrochloride - J61536 - Alfa Aesar

J61536 O-Acetyl-L-carnitine hydrochloride

CAS Number
5080-50-2
Synonyms
(R)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride
L-Carnitine acetyl ester hydrochloride

Size Price ($) Quantity Availability
5g 81.60
25g 276.00
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O-Acetyl-L-carnitine hydrochloride

MDL
MFCD00082230

Chemical Properties

Formula
C9H17NO4•HCl
Formula Weight
239.70
Form
White crystalline powder
Sensitivity
Hygroscopic
Solubility
Soluble in water (100 mg/ml), alcohol, and ethanol (10%). Insoluble in ether.

Applications

O-Acetyl-L-carnitine hydrochloride is used as a cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Hygroscopic. Keep away from strong oxidizing agents.

Literature References

Stieger, B.; O'Neill, B.; Krähenbühl, S. Characterization of L-carnitine transport by rat kidney brush-border-membrane vesicles. Biochem J . 1995, 309, ( Pt 2), 643-647.

Fu, L.; Huang, M.; and Chen.; S. Primary carnitine deficiency and cardiomyopathy. Korean Circ J. 2013, 43, ( 12), 785-792.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,84
Beilstein
4340103
Harmonized Tariff Code
2922.49
TSCA
No

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