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HEPES hemisodium salt is common buffer for biological sciences, particularly used in cell culture to maintain physiological pH. It acts a buffering component, which is used in the preparation of buffers. It is described as one of the best all-purpose buffers available for use in biological research.
Kebede, N.; Francis, P. S.; Barbante, G. J.; Hogan, C. F. Electrogenerated chemiluminescence of tris(2, 2' bipyridine)ruthenium(II) using common biological buffers as co-reactant, pH buffer and supporting electrolyte. Analyst 2015, 140 (21), 7142-7145.
Flourat, A. L.; Peru, A. A. M.; Teixeira, A. R. S.; Brunissen, F.; Allais, F. Chemo-enzymatic synthesis of key intermediates (S)-γ-hydroxymethyl-α, β-butenolide and (S)-γ-hydroxymethyl-γ-butyrolactone via lipase-mediated Baeyer-Villiger oxidation of levoglucosenone. Green Chem. 2015, 17 (1), 404-412.