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J61905 Mycophenolic acid, 98%

CAS Number
24280-93-1
Synonyms

Stock No. Size Price ($) Quantity Availability
J61905-03 1g 35.70
J61905-06 5g 100.00
J61905-09 10g 174.00
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Mycophenolic acid, 98%

MDL
MFCD00036814
EINECS
246-119-3

Chemical Properties

Formula
C17H20O6
Formula Weight
320.34
Form
Powder
Melting point
139-141°
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in methanol at 50mg/ml

Applications

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agent.

Literature References

Eugui et al. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depeletion. Scand.J.Immunol. 1991, 33, (2), 161-73.

Allison et al. Mechanisms of action of mycophenolic acid. Ann.N.Y.Acad.Sci. 1993, 696, 63-87.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H341-H360

Harmful if swallowed. Suspected of causing genetic defects. May damage fertility or the unborn child.

Precautionary Statements: P201-P280-P301+P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6327
Beilstein
1295848
Hazard Class
9
Packing Group
III
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
MP8050000

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