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24280-93-1 - Mycophenolic acid, 98% - J61905 - Alfa Aesar

J61905 Mycophenolic acid, 98%

CAS Number
24280-93-1
Synonyms

Size Price ($) Quantity Availability
1g 34.71
5g 77.12
10g 173.04
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Mycophenolic acid, 98%

MDL
MFCD00036814
EINECS
246-119-3

Chemical Properties

Formula
C17H20O6
Formula Weight
320.34
Form
Powder
Melting point
139-141°
Solubility
Soluble in methanol at 50mg/ml

Applications

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agent.

Literature References

Eugui et al. Lymphocyte-selective cytostatic and immunosuppressive effects of mycophenolic acid in vitro: role of deoxyguanosine nucleotide depeletion. Scand.J.Immunol. 1991, 33, (2), 161-73.

Allison et al. Mechanisms of action of mycophenolic acid. Ann.N.Y.Acad.Sci. 1993, 696, 63-87.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P264-P270-P301+P312-P330-P501a

Wash thoroughly after handling. Do not eat, drink or smoke when using this product. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,6327
Beilstein
1295848
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
MP8050000

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