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117946-91-5 - Luzindole, 97% - N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide - N-Acetyl-2-benzyltryptamine - J61915 - Alfa Aesar

J61915 Luzindole, 97%

CAS Number
117946-91-5
Synonyms
N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide
N-Acetyl-2-benzyltryptamine

Size Price ($) Quantity Availability
5mg 98.37
25mg 359.20
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Luzindole, 97%

MDL
MFCD00672498

Chemical Properties

Formula
C19H20N2O
Formula Weight
292.37
Form
Powder
Melting point
44-46°
Solubility
Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water.

Applications

Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

Notes

Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.

Literature References

C Browning; I Beresford; N Fraser, H Giles. Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors. British Journal of Pharmacology. 2000, 129, (5), 877-886.

M L Dubocovich. Luzindole (N-0774): a novel melatonin receptor antagonist. Journal of Pharmacology and Experimental Therapeutics. 1988, 246, (3), 902-910.

Other References

Harmonized Tariff Code
2933.99
TSCA
No

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