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56392-17-7 - Metoprolol tartrate, 98+% - (±)1-(Isopropylamino)-3-[4-(beta-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt - J61920 - Alfa Aesar

J61920 Metoprolol tartrate, 98+%

CAS Number
56392-17-7
Synonyms
(±)1-(Isopropylamino)-3-[4-(beta-methoxyethyl)phenoxy]-2-propanol (+)-tartrate salt

Size Price ($) Quantity Availability
5g 58.81
25g 246.00
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Metoprolol tartrate, 98+%

MDL
MFCD00056257
EINECS
260-148-9

Chemical Properties

Formula
(C15H25NO3)2.C4H6O6
Formula Weight
684.82
Form
Powder
Melting point
120°
Solubility
Soluble in water (>1000 mg/ml), methanol (>500 mg/ml), chloroform (496 mg/ml), ethanol (31 mg/ml at 25°C), and DMSO (100 mg/ml at 25°C).

Applications

Metoprolol tartrate is an antagonist of the β1-AR (β1-adrenoceptor). It inhibits spontaneous endothelin-1 production in vitro and displays antihypertensive and antianginal activity in vivo.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents.

Literature References

Jef Stappaerts; Benjamin Wuyts; Jan Tack; Pieter Annaert; Patrick Augustijns. Human and simulated intestinal fluids as solvent systems to explore food effects on intestinal solubility and permeability. European Journal of Pharmaceutical Sciences. 2012, 63,

Moran Zur; Allison S. Hanson; Arik Dahan. The complexity of intestinal permeability: Assigning the correct BCS classification through careful data interpretation. European Journal of Pharmaceutical Sciences. 2014, 61, 11-17.

Other References

Merck
14,6151
Harmonized Tariff Code
2922.19
TSCA
No
RTECS
UB7450100

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