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J62079 Retinol, 95%, synthetic

CAS Number
68-26-8
Synonyms
Vitamin A alcohol

Stock No. Size Price ($) Quantity Availability
J62079-MC 100mg 50.90
J62079-MD 250mg 78.10
J62079-ME 500mg 128.00
J62079-03 1g 217.00
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Retinol, 95%, synthetic

MDL
MFCD00001552
EINECS
200-683-7

Chemical Properties

Formula
C20H30O
Formula Weight
286.46
Form
Crystalline solid
Storage & Sensitivity
Store at -20°C. Moisture Sensitive. Light Sensitive. Store under Nitrogen.
Solubility
Practically insoluble in water or glycerol; soluble in absolute alcohol, methanol, chloroform, ether, fats and oils.

Applications

It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Air and moisture sensitive. Store under nitrogen. Keep away from strong oxidizing agents.

Literature References

Arora A.; Willhite CA.; Liebler DC. Interactions of beta-carotene and cigarette smoke in human bronchial epithelial cells. Carcinogenesis. 2001, 22, (8), 1173-1178.

French AL.; Kirstein LM.; Massad LS.; et al. Association of vitamin A deficiency with cervical squamous intraepithelial lesions in human immunodeficiency virus-infected women. J Infect Dis. 2000, 182, (4), 1084-1089.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319-H361d-H500

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. Suspected of damaging the unborn child. May form combustible dust concentrations in air

Precautionary Statements: P201-P202-P264b-P270-P280-P280i-P301+P312-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P337+P313-P362-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. Wear eye/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF exposed or concerned: Get medical advice/attention. Rinse mouth. If skin irritation occurs: If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,10013
Beilstein
403040
Harmonized Tariff Code
2936.21
TSCA
Yes
RTECS
VH6750000

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