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68-26-8 - Retinol, 95%, synthetic - Vitamin A alcohol - J62079 - Alfa Aesar

J62079 Retinol, 95%, synthetic

CAS Number
68-26-8
Synonyms
Vitamin A alcohol

Size Price ($) Quantity Availability
100mg 49.90
250mg 75.00
500mg 120.00
1g 195.00
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Retinol, 95%, synthetic

MDL
MFCD00001552
EINECS
200-683-7

Chemical Properties

Formula
C20H30O
Formula Weight
286.46
Form
Crystalline solid
Sensitivity
Moisture & Light Sensitive
Solubility
Practically insoluble in water or glycerol; soluble in absolute alcohol, methanol, chloroform, ether, fats and oils.

Applications

It induces cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. It plays an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. It acts as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR) that act as transcription factors to regulate the growth and differentiation of normal and malignant cells.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Air and moisture sensitive. Store under nitrogen. Keep away from strong oxidizing agents.

Literature References

Arora A.; Willhite CA.; Liebler DC. Interactions of beta-carotene and cigarette smoke in human bronchial epithelial cells. Carcinogenesis. 2001, 22, (8), 1173-1178.

French AL.; Kirstein LM.; Massad LS.; et al. Association of vitamin A deficiency with cervical squamous intraepithelial lesions in human immunodeficiency virus-infected women. J Infect Dis. 2000, 182, (4), 1084-1089.

GHS Hazard and Precautionary Statements

Hazard Statements: H360-H302-H319-H317

May damage fertility or the unborn child. Harmful if swallowed. Causes serious eye irritation. May cause an allergic skin reaction.

Precautionary Statements: P201-P261-P280-P281-P305+P351+P338-P301+P312-P363-P308+P313-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,10013
Beilstein
403040
Harmonized Tariff Code
2936.21
TSCA
Yes
RTECS
VH6750000

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