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316-46-1 - 5-Fluorouridine, 97% - J62083 - Alfa Aesar

J62083 5-Fluorouridine, 97%

CAS Number
316-46-1
Synonyms

Size Price ($) Quantity Availability
1g 49.10
5g 197.00
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5-Fluorouridine, 97%

MDL
MFCD00036832
EINECS
206-260-3

Chemical Properties

Formula
C9H11FN2O6
Formula Weight
262.19
Form
Powder
Solubility
Soluble in Methanol (Slightly), Water (Slightly).

Applications

5-Fluorouridine exhibits anticancer activity. It is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs. It is an active metabolite of Doxifluridine.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agents. Store at 4°C.

Literature References

Ales Obrdlik; Piergiorgio Percipalle. The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation. Nucleus (Austin, Tex. : Print).2011, 2, (1), 72-79.

P V Sahasrabudhe; R T Pon, W H Gmeiner. Effects of site-specific substitution of 5-fluorouridine on the stabilities of duplex DNA and RNA. Nucleic Acids Research.1995, 23, (19), 3916-3921.

GHS Hazard and Precautionary Statements

Hazard Statements: H341

Suspected of causing genetic defects.

Precautionary Statements: P201-P280-P202-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
33662
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
YU8050000

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