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3102-56-5 - DL-erythro-Dihydrosphingosine - DL-Sphinganine - (2R*,3S*)-(±)-2-Aminooctadecane-1,3-diol - J62103 - Alfa Aesar

J62103 DL-erythro-Dihydrosphingosine

CAS Number
3102-56-5
Synonyms
DL-Sphinganine
(2R*,3S*)-(±)-2-Aminooctadecane-1,3-diol

Size Price ($) Quantity Availability
50mg 538.00
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DL-erythro-Dihydrosphingosine

MDL
MFCD00079141

Chemical Properties

Formula
C18H39NO2
Formula Weight
301.51
Form
Powder
Solubility
Soluble in water (partly miscible), chloroform, 100% warm ethanol (25 mg/ml), warm DMSO (25 mg/ml), and methanol.

Applications

DL-erythro-Dihydrosphingosine is an inhibitor of PKC (protein kinase C). This compound also blocks PLA2 (phospholipases A2) and the D-sphingosine precursor.

Notes

Protect from heat. Incompatible with heat and oxidizing agents. Store at -20°C.

Literature References

B.Y.M. Yung; E.K.W. Hui. Differential Regulation of Protein Kinase C Isoenzymes during Sphinganine Potentiation of Retinoic Acid-Induced Granulocytic Differentiation in Human Leukemia HL-60 Cells. Biochemical and Biophysical Research Communications. 1993, 196, 1390-1400.

GHS Hazard and Precautionary Statements

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
1724234
Harmonized Tariff Code
2922.19
TSCA
No

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