Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

J62163 Calciferol, 97%

CAS Number
50-14-6
Synonyms
Ergocalciferol
Vitamin D2

Stock No. Size Price ($) Quantity Availability
J62163-03 1g 23.20
J62163-06 5g 91.70
Add to Cart Add to Quote Request View Item

Calciferol, 97%

MDL
MFCD00166988
EINECS
200-014-9

Chemical Properties

Formula
C28H44O
Formula Weight
396.66
Form
Powder
Melting point
118-119°
Storage & Sensitivity
Keep Cold.
Solubility
Soluble in ethanol (80 mg/ml at 25°C), water (<1 mg/ml at 25°C), methanol, DMF (~20 mg/ml), and DMSO (20 mg/ml at 25°C).

Applications

Calciferol has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Calciferol has also been shown to be an inhibitor of DNA polymerase. Calciferol with calcium is used to treat or prevent bone loss (osteoporosis). Calciferol is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It is often used in kidney disease to keep calcium levels normal and allow normal bone growth.

Notes

To verify quality:
  • Dissolve about 0.5mg of calciferol into 5mL chloroform, add 0.3mL acetic anhydride and 0.1mL sulfuric acid, shake and mix vigorously. The mixture is initially produced bright red color, and then rapidly changes violet and finally blue to green.
  • Dissolve 10mg of calciferol into 2mL of 90% ethanol, add 2mL solution of digitalis saponin and incubate for 18h. No precipitation or cloud should be observed.

Contains no Ergosterol.

Literature References

Gui-Dong. Zhu.; William H. Okamura. Synthesis of Vitamin D (Calciferol).Chem. Rev. 1995, 95 (6),1877-1952 .

Maryka H. Bhattacharyya.; H.F. DeLuca. Subcellular location of rat liver calciferol-25-hydroxylase. Arch. Biochem. Biophys. 1974, 160 (1),58-62 .

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H311-H330-H372

Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. Causes damage to organs through prolonged or repeated exposure.

Precautionary Statements: P301+P310a-P304+P340-P320-P330-P405-P501a

IF SWALLOWED: Immediately call a POISON CENTER/doctor IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,10018
Beilstein
1916682
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2936.29
TSCA
Yes
RTECS
KE1050000

Recommended

  • H33952

    2-Fluoro-4-(pentafluorothio)benzamide, 97%
  • H52755

    3-(trans-3-Ethoxy-3-oxo-1-propen-1-yl)benzeneboronic acid, 98%
  • J66249

    Bone Gla Protein (45-49)
  • J67078

    D-myo-Inositol-2,4-bisphosphate sodium salt
  • 45096

    Tin shot, 3.175mm (0.125in) & down, 99% (metals basis)

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware