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Calciferol has a strong inhibitory effect against bladder tumor promotion by sodium saccharin and induces cell differentiation in leukemia cells. Calciferol has also been shown to be an inhibitor of DNA polymerase. Calciferol with calcium is used to treat or prevent bone loss (osteoporosis). Calciferol is also used with other medications to treat low levels of calcium or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It is often used in kidney disease to keep calcium levels normal and allow normal bone growth.
Contains no Ergosterol.
Gui-Dong. Zhu.; William H. Okamura. Synthesis of Vitamin D (Calciferol).Chem. Rev. 1995, 95 (6),1877-1952 .
Maryka H. Bhattacharyya.; H.F. DeLuca. Subcellular location of rat liver calciferol-25-hydroxylase. Arch. Biochem. Biophys. 1974, 160 (1),58-62 .
Hazard Statements: H301-H311-H330-H372
Toxic if swallowed. Toxic in contact with skin. Fatal if inhaled. Causes damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P264b-P270-P271-P280-P284-P301+P310-P302+P352-P304+P340-P310-P312-P314-P330-P361-P363-P501c
Do not breathe dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Get medical advice/attention if you feel unwell. Rinse mouth. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant