Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

J62200 Danazol

CAS Number
17230-88-5
Synonyms
17beta-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole
2,4,17a-Pregnadien-20-yno[2,3-d]isoxazol-17-ol

Stock No. Size Price ($) Quantity Availability
J62200-MC 100mg 46.80
J62200-ME 500mg 189.00
Add to Cart Bulk/Specialty Print Quote View Item

Danazol

MDL
MFCD00056838
EINECS
241-270-1

Chemical Properties

Formula
C22H27NO2
Formula Weight
337.46
Form
Powder
Melting point
218-220°
Storage & Sensitivity
Store at -20°C.
Solubility
Partly soluble in water. Soluble in chloroform (25 mg/ml), acetone, acetonitrile, and ethanol. 17beta-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole and 2,4,17a-Pregnadien-20-yno[2,3-d]isoxazol-17-ol are the synonym of this compound.

Applications

Danazol is a synthetic gonadotropin inhibitor which has a preventive effect on estrogen -related endometrial carcinogenesis in mice. Danazol therapy has also shown regression of established mammary carcinoma in rats. This medication is used in women to treat pelvic pain and infertility due to a certain uterus disorder (endometriosis) and also to treat breast pain/tenderness/nodules due to a certain breast condition (fibrocystic breast disease). It is also used in both men and women to prevent swelling of the abdomen/arms/legs/face/airway due to a certain congenital disease

Notes

Store at room temperature. Incompatible with oxidizing agents.

Literature References

Gary G. Liversidge.; Kenneth C. Cundy. Particle size reduction for improvement of oral bioavailability of hydrophobic drugs: I. Absolute oral bioavailability of nanocrystalline danazol in beagle dogs.Int. J. Pharm. 1995, 125 (1),91-97 .

GHS Hazard and Precautionary Statements

Hazard Statements: H312+H332-H361

Harmful in contact with skin. Harmful if inhaled. Suspected of damaging fertility or the unborn child.

Precautionary Statements: P201-P202-P271-P281-P302+P352-P304+P340-P308+P313-P312-P363-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,2812
Harmonized Tariff Code
2937.29
TSCA
No
RTECS
TU4157070

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware