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Measurement of NUA levels in urine is used to indicate possible elevated nicotinamide adenine dinucleotide (NAD) catabolism. NUA may be used as a reference (standard curve) in analysis of NAD and NUA catabolism. It is an antiproliferative.
N Hengen.; V Seiberth.; M Hengen. High-performance liquid-chromatographic determination of free nicotinic acid and its metabolite, nicotinuric acid, in plasma and urine.Clin. Chem. 1978, 24 (10),1740-1743 .
P. Pfuhl.; U. Kärcher.; N. Häring.; A. Baumeister.; Mona Abdel Tawab.; M. Schubert-Zsilavecz. Simultaneous determination of niacin, niacinamide and nicotinuric acid in human plasma.J. Pharm. Biomed. Anal. 2005, 36 (5),1045-1052 .