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9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. 9-cis-Retinoic acid is an inhibitor of Cox-2 and an activator of RAR α, RAR β, RAR γ and RXR.
SA Kliewer.; K Umesono.; DJ Noonan.; RA Heyman. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature. 1992, 358, 771 - 774.
RA Heyman.; DJ Mangelsdorf.; JA Dyck.; RB Stein. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell. 1992, 68, (2), 397-406.
Hazard Statements: H335-H360D
May cause respiratory irritation. May damage the unborn child.
Precautionary Statements: P201-P202-P271-P281-P304+P340-P308+P313-P501c
Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant