Cookies disclaimer

I agree Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. You can disable the usage of cookies by changing the settings of your browser. By browsing our website without changing the browser settings you grant us permission to store that information on your device.

J62219 9-cis-Retinoic acid

CAS Number
5300-03-8
Synonyms

Stock No. Size Price ($) Quantity Availability
J62219-#0 5mg 222.00
Add to Cart Bulk/Specialty Print Quote View Item

9-cis-Retinoic acid

MDL
MFCD00270072

Chemical Properties

Formula
C20H28O2
Formula Weight
300.44
Form
Powder
Melting point
178-180°
Storage & Sensitivity
Store at -20°C. Moisture Sensitive. Light Sensitive. Store under Nitrogen.
Solubility
Soluble in chloroform (50 mg/ml), DMSO (~25 mg/ml), ethanol (25 mg/ml), and acetone (25 mg/ml). Insoluble in water.

Applications

9-cis-Retinoic acid is a vitamin A analog that inhibits cell proliferation and induces cell differentiation. 9-cis-Retinoic acid is an inhibitor of Cox-2 and an activator of RAR α, RAR β, RAR γ and RXR.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.

Literature References

SA Kliewer.; K Umesono.; DJ Noonan.; RA Heyman. Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature. 1992, 358, 771 - 774.

RA Heyman.; DJ Mangelsdorf.; JA Dyck.; RB Stein. 9-cis retinoic acid is a high affinity ligand for the retinoid X receptor. Cell. 1992, 68, (2), 397-406.

GHS Hazard and Precautionary Statements

Hazard Statements: H335-H360D

May cause respiratory irritation. May damage the unborn child.

Precautionary Statements: P201-P202-P271-P281-P304+P340-P308+P313-P501c

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Use only outdoors or in a well-ventilated area. Use personal protective equipment as required. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF exposed or concerned: Get medical advice/attention. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,249
Harmonized Tariff Code
2936.21
TSCA
No
RTECS
VH6450000

Recommended

Recently Viewed

Chemicals

Life Science

Metals & Materials

Catalysts

Analytical & Labware