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A calcium channel antagonist with potent antioxidant activityAmlodipine is an L-type calcium channel protein inhibitor and blocker. It is used in combination with the angiotensin receptor blocker olmesartan. Further, it acts as a dihydropyridine calcium channel blocker. It is used as an anti-hypertensive. It is involved in the treatment of angina and to lower blood pressure. In addition to this, it is used to prevent chest pain and in coronary artery disease.
Akamine, Y.; Uehara, H.; Miura, M.; Yasui-Furukori, N.; Uno, T. Multiple inductive effects of carbamazepine on combined therapy with paliperidone and amlodipine. J. Clin. Pharm. Ther. 2015, 40 (4), 480-482.
Norouzi, P.; Gupta, V. K.; Larijani, B.; Rasoolipour, S.; Faridbod, F.; Ganjali, M. R. Coulometric differential FFT admittance voltammetry determination of Amlodipine in pharmaceutical formulation by nano-composite electrode. Talanta 2015, 131, 577-584.
Hazard Statements: H301-H318-H373
Toxic if swallowed. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure.
Precautionary Statements: P260-P280i-P301+P310a-P305+P351+P338-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Wear eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.