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88150-42-9 - Amlodipine, 97+% - UK-48340 - J62242 - Alfa Aesar

J62242 Amlodipine, 97+%

CAS Number
88150-42-9
Synonyms
UK-48340

Size Price ($) Quantity Availability
1g 106.09
5g 407.88
10g 413.60
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Amlodipine, 97+%

MDL
MFCD00864687
EINECS
425-820-1

Chemical Properties

Formula
C20H25ClN2O5
Formula Weight
408.88
Form
Crystalline powder
Melting point
134-136°
Solubility
Soluble in dimethyl sulfoxide, ethanol, water, dimethyl formamide, acetone, chloroform, ethyl acetate and methanol.

Applications

A calcium channel antagonist with potent antioxidant activityAmlodipine is an L-type calcium channel protein inhibitor and blocker. It is used in combination with the angiotensin receptor blocker olmesartan. Further, it acts as a dihydropyridine calcium channel blocker. It is used as an anti-hypertensive. It is involved in the treatment of angina and to lower blood pressure. In addition to this, it is used to prevent chest pain and in coronary artery disease.

Notes

Incompatible with oxidizing agents.

Literature References

Akamine, Y.; Uehara, H.; Miura, M.; Yasui-Furukori, N.; Uno, T. Multiple inductive effects of carbamazepine on combined therapy with paliperidone and amlodipine. J. Clin. Pharm. Ther. 2015, 40 (4), 480-482.

Norouzi, P.; Gupta, V. K.; Larijani, B.; Rasoolipour, S.; Faridbod, F.; Ganjali, M. R. Coulometric differential FFT admittance voltammetry determination of Amlodipine in pharmaceutical formulation by nano-composite electrode. Talanta 2015, 131, 577-584.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H318-H373-H400-H410

Toxic if swallowed. Causes serious eye damage. May cause damage to organs through prolonged or repeated exposure. Very toxic to aquatic life. Very toxic to aquatic life with long lasting effects.

Precautionary Statements: P260-P273-P280-P264-P301+P310-P305+P351+P338-P310-P321-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. Wash thoroughly after handling. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,491
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
US7968329

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