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28395-03-1 - Bumetanide, 98+% - 3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid - J62302 - Alfa Aesar

J62302 Bumetanide, 98+%

CAS Number
28395-03-1
Synonyms
3-(Aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid

Size Price ($) Quantity Availability
1g 93.90
5g 365.00
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Bumetanide, 98+%

MDL
MFCD00078949
EINECS
249-004-6

Chemical Properties

Formula
C17H20N2O5S
Formula Weight
364.40
Form
Solid
Melting point
230-231°
Solubility
Soluble in ethanol (10 mg/ml), DMSO (25 mg/ml), acetone, benzene, methanol, propylene glycol, and water (<1 mg/ml).

Applications

Bumetanide has been observed to block the depolarization of GABA in cortical development studies. It is been used as a specific inhibitor of Na+-K+-2Cl- cotransporter NKCC1

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from acids.

Literature References

Star, R.A., et al. Luminal disequilibrium pH and ammonia transport in outer medullary collecting duct. Am. J. Physiol. 1987, 252( 6 Pt 2), F1148-F1157.

O'Grady, S.M., et al. Characteristics and functions of Na-K-Cl cotransport in epithelial tissues. Am. J. Physiol. 1987, 253( 2 Pt 1), C177-C192.

Other References

Merck
14,1484
Harmonized Tariff Code
2935.90
TSCA
No
RTECS
DG4910000

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