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Valinomycin, is used as a potassium ionophore shown to induce cell death. Due to the ion-selective nature of valinomycin, it is used in ion-selective electrodes.
Marques-Santos, L.F., et al. Cyclosporin A does not protect the disruption of the inner mitochondrial membrane potential induced by potassium ionophores in intact K562 cells. Cell Biol. Int. 2006, 30( 3), 197-204.
Abdalah, R., et al. Valinomycin-induced apoptosis in Chinese hamster ovary cells. Neurosci. Lett. 2006, 405( 1-2), 68-73.
Hazard Statements: H300-H310
Fatal if swallowed. Fatal in contact with skin.
Precautionary Statements: P262-P264b-P270-P280-P301+P310-P302+P350-P310-P330-P361-P363-P501c
Do not get in eyes, on skin, or on clothing. Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF ON SKIN: Gently wash with plenty of soap and water. Rinse mouth. Remove/Take off immediately all contaminated clothing. Wash contaminated clothing before reuse. Dispose of contents/ container to an approved waste disposal plant