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Valinomycin, is used as a potassium ionophore shown to induce cell death. Due to the ion-selective nature of valinomycin, it is used in ion-selective electrodes.
Marques-Santos, L.F., et al. Cyclosporin A does not protect the disruption of the inner mitochondrial membrane potential induced by potassium ionophores in intact K562 cells. Cell Biol. Int. 2006, 30( 3), 197-204.
Abdalah, R., et al. Valinomycin-induced apoptosis in Chinese hamster ovary cells. Neurosci. Lett. 2006, 405( 1-2), 68-73.
Hazard Statements: H300-H310
Fatal if swallowed. Fatal in contact with skin.
Precautionary Statements: P262-P280h-P301+P310a-P321-P405-P501a
Do not get in eyes, on skin, or on clothing. Wear protective gloves/clothing. IF SWALLOWED: Immediately call a POISON CENTER/doctor Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.