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71-62-5 - Veratridine, 97+% - 3-Veratroylveracevine - J62324 - Alfa Aesar

J62324 Veratridine, 97+%

CAS Number
71-62-5
Synonyms
3-Veratroylveracevine

Size Price ($) Quantity Availability
10mg 101.70
50mg 450.05
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Veratridine, 97+%

MDL
MFCD00082515
EINECS
200-758-4

Chemical Properties

Formula
C36H51NO11
Formula Weight
673.80
Form
Powder
Solubility
Soluble in ethanol or DMSO. Freely soluble in chloroform. Also soluble in 1M HCl

Applications

Veratridine causes Na+ channels to stay open during a sustained membrane depolarization by abolishing inactivation. This, in turn, opens voltage-activated calcium channels, thus increasing intracellular calcium content and inducing neurotransmitter release. Alkaloid neurotoxin which depolarizes excitable tissue; used to increase membrane sodium permeability.

Notes

Store at -20°C. Incompatible with oxidizing agents. Protect from heat.

Literature References

Stephen R. Skilling.; David H. Smullin.; Alvin J. Beitz.; Alice A. Larson. Extracellular Amino Acid Concentrations in the Dorsal Spinal Cord of Freely Moving Rats Following Veratridine and Nociceptive Stimulation.J. Neurochem. 1988, 51 (1),127-132 .

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H310-H330-H315-H319-H335

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P260-P284-P301+P310-P304+P340-P305+P351+P338-P320-P330-P361-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,9954
Beilstein
78875
Hazard Class
6.1
Packing Group
I
Harmonized Tariff Code
2939.99
TSCA
No
RTECS
YX5600000

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