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20350-15-6 - Brefeldin A, 99% - J62340 - Alfa Aesar

J62340 Brefeldin A, 99%

CAS Number
20350-15-6
Synonyms

Size Price ($) Quantity Availability
10mg 104.00
25mg 230.00
50mg 381.00
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Brefeldin A, 99%

MDL
MFCD00083258

Chemical Properties

Formula
C16H24O4
Formula Weight
280.36
Form
Crystalline powder
Melting point
201-205°
Solubility
Soluble in dimethylsulfoxide, dichloromethane and ethanol. Slightly soluble in water.

Applications

Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.

Notes

Store in cool place. Incompatible with strong oxidizing agents.

Literature References

Wase, N.; Tu, B.; Black, P. N.; DiRusso, C. C. Phenotypic screening identifies Brefeldin A/Ascotoxin as an inducer of lipid storage in the algae Chlamydomonas reinhardtii. Algal Res. 2015, 11, 74-84.

Fuchs, M.; Fîrstner, A. trans-Hydrogenation: Application to a Concise and Scalable Synthesis of Brefeldin A. Angew. Chem. 2015, 54 (13), 3978 -3982.

GHS Hazard and Precautionary Statements

Hazard Statements: H302

Harmful if swallowed.

Precautionary Statements: P260u-P201-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1369
Beilstein
25191
Harmonized Tariff Code
2941.90
TSCA
No
RTECS
GY8410000

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