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J62374 beta-Endorphin, human

CAS Number
61214-51-5
Synonyms

Stock No. Size Price ($) Quantity Availability
J62374-M^ 1mg 183.00
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beta-Endorphin, human

MDL
MFCD00076383

Chemical Properties

Formula
C158H251N39O46S
Formula Weight
3465.06
Form
Powder
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water.

Applications

beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both pre- and post- synaptic nerve terminals, primarily exerting their effect through presynaptic binding. In the central nervous system, beta-endorphins similarly bind mu-opioid receptors and exert their primary action at presynaptic nerve terminals. It is a potent pain suppressant.

Notes

Store at 4 degree C for short term (weeks) and -20 degree C for long term.

Literature References

Y Hosobuchi.; J Rossier.; FE Bloom.; R Guillemin. Stimulation of human periaqueductal gray for pain relief increases immunoreactive beta-endorphin in ventricular fluid.Science. 1979, 203 ( 4377),279-281 .

L. Grandison.; A. Guidotti. Stimulation of food intake by muscimol and beta endorphin. Neuropharmacology. 1977, 16 (1-2), 533-536.

Other References

Harmonized Tariff Code
2937.19
TSCA
No

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