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9001-12-1 - Collagenase, Type I, Clostridium histolyticum - J62406 - Alfa Aesar

J62406 Collagenase, Type I, Clostridium histolyticum

CAS Number

Size Price ($) Quantity Availability
100mg 49.50
1g 234.00
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Collagenase, Type I, Clostridium histolyticum


Chemical Properties

Soluble in aqueous buffers.


Collagenase, Type I, Clostridium histolyticum is used as a powder and solvent injection kit for the treatment of dupuytren's contracture.


Minimum 125 units per mg protein. One unit releases one micromole of L-leucine equivalents from collagen in 5 hours at 37 degrees and pH 7.5Hygroscopic. Stable at normal temperatures and pressures.

Literature References

Furusawa, K.; Mizutani, T.; Machino, H.; Yahata, S.; Fukui, A.; Sasaki, N. Application of Multichannel Collagen Gels in Construction of Epithelial Lumen-like Engineered Tissues. ACS Biomater. Sci. Eng. 2015, 1 (7), 538-548.

Nakayama, K. H.; Hong, G.; Lee, J. C.; Patel, J.; Edwards, B.; Zaitseva, T. S.; Paukshto, M. V.; Dai, H.; Cooke, J. P.; Woo, Y. J.; Huang, N. F. Aligned-Braided Nanofibrillar Scaffold with Endothelial Cells Enhances Arteriogenesis. ACS Nano. 2015, 9 (7), 6900-6908.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H315-H319-H317-H335

May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation.

Precautionary Statements: P285-P261-P280-P305+P351+P338-P304+P340-P342+P311-P362-P312-P405-P501a

In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code


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