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J62406 Collagenase, Type I, Clostridium histolyticum

CAS Number

Stock No. Size Price ($) Quantity Availability
J62406-MC 100mg 51.00
J62406-03 1g 239.00
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Collagenase, Type I, Clostridium histolyticum


Chemical Properties

Storage & Sensitivity
Keep Cold.
Soluble in aqueous buffers.


Collagenase, Type I, Clostridium histolyticum is used as a powder and solvent injection kit for the treatment of dupuytren's contracture.


Minimum 125 units per mg protein. One unit releases one micromole of L-leucine equivalents from collagen in 5 hours at 37 degrees and pH 7.5Hygroscopic. Stable at normal temperatures and pressures.

Literature References

Furusawa, K.; Mizutani, T.; Machino, H.; Yahata, S.; Fukui, A.; Sasaki, N. Application of Multichannel Collagen Gels in Construction of Epithelial Lumen-like Engineered Tissues. ACS Biomater. Sci. Eng. 2015, 1 (7), 538-548.

Nakayama, K. H.; Hong, G.; Lee, J. C.; Patel, J.; Edwards, B.; Zaitseva, T. S.; Paukshto, M. V.; Dai, H.; Cooke, J. P.; Woo, Y. J.; Huang, N. F. Aligned-Braided Nanofibrillar Scaffold with Endothelial Cells Enhances Arteriogenesis. ACS Nano. 2015, 9 (7), 6900-6908.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H317-H319-H334-H335

Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P337+P313-P342+P311-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Contaminated work clothing should not be allowed out of the workplace. Wear protective gloves/protective clothing/eye protection/face protection. In case of inadequate ventilation wear respiratory protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation or rash occurs: Get medical advice/attention. If eye irritation persists: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

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