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57444-62-9 - Resiniferatoxin, 99+% - J62458 - Alfa Aesar

J62458 Resiniferatoxin, 99+%

CAS Number
57444-62-9
Synonyms

Size Price ($) Quantity Availability
1mg 101.00
5mg 407.00
10mg 721.00
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Resiniferatoxin, 99+%

MDL
MFCD00135927

Chemical Properties

Formula
C37H40O9
Formula Weight
628.71
Form
Solid
Solubility
Soluble in DMSO to 100mM and to 50mM in ethanol

Applications

Resiniferatoxin, a potent capsaicin-like stimulator of peripheral nociceptors in the neonatal rat tail in vitro. Resiniferatoxin is used as an anti-inflammatory, anti-viral and anti-psoriatic uses. Diterpene ester related to phorbol but apparently not tumorigenic activates protein kinase C

Notes

Resiniferatoxin (RTX) is susceptible to slow degradation if exposed to air. Even at -20°C, Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep in a dry place. Keep away from strong oxidizing agents. RTX must be stored in an inert atmosphere for long-term stability.

Literature References

Szolcsanyi et al. Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons. J.Pharmacol.Exp.Ther. 1990, 255, (2), 923-8.

Winter et al. Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin. Brain Res. 1990, 520, (1-2), 131-40.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280-P301+P310-P305+P351+P338-P304+P340-P362-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Beilstein
5371150
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
3002.90
TSCA
No
RTECS
CY1633700

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