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2058-46-0 - Oxytetracycline hydrochloride - J62489 - Alfa Aesar

J62489 Oxytetracycline hydrochloride

CAS Number
2058-46-0
Synonyms

Size Price ($) Quantity Availability
25g 59.20
100g 178.00
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Oxytetracycline hydrochloride

MDL
MFCD00135815
EINECS
218-161-2

Chemical Properties

Formula
C22H24N2O9•HCl
Formula Weight
496.90
Form
Crystalline powder
Melting point
180°
Sensitivity
Air & Light Sensitive
Solubility
Soluble in ethanol

Applications

Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome- lysosome (P-L) fusion in P388D1 cells1 and antibiotic susceptibilities of Mycoplasma bovis isolates.

Notes

Concentrated aqueous solutions at neutral pH will hydrolyze oxytetracycline and cause it to precipitate

Literature References

M Y Wells and Y Rikihisa. Lack of lysosomal fusion with phagosomes containing Ehrlichia risticii in P388D1 cells: abrogation of inhibition with oxytetracycline.. Infection and Immunity. 1988, 56, (12), 3209-3215.

A Thomas et. al. Antibiotic susceptibilities of recent isolates of Mycoplasma bovis in Belgium. Veterinary Record. 2003, 153, (14), 428-431.

Other References

Merck
14,6976
Beilstein
3853107
Harmonized Tariff Code
2941.30
TSCA
Yes
RTECS
QI8225000

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