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108321-42-2 - G418 disulfate, Cell Culture Reagent - Geneticin disulfate - J62671 - Alfa Aesar

J62671 G418 disulfate, Cell Culture Reagent

CAS Number
108321-42-2
Synonyms
Geneticin disulfate

Size Price ($) Quantity Availability
1g 70.30
5g 285.00
25g 824.00
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G418 disulfate, Cell Culture Reagent

MDL
MFCD00058314

Chemical Properties

Formula
C20H40N4O10•2H2SO4
Formula Weight
692.71
Form
Powder
Solubility
Soluble in water.

Applications

G418 disulfate is an aminoglycoside that is toxic to bacteria, yeast, protozoans and helminths. It prevents protein synthesis by blocking the elongation step in prokaryotic and eukaryotic ribosomes. It is used as a selection agent for G418 resistant bacteria or fungi after transformation.

Notes

Incompatible with oxidizing agents. Store in a cool place.

Literature References

Lemke, K.; Förster, T.; Römer, R.; Quade, M.; Wiedemeier, S.; Grodrian, A.; Gastrock, G. A modular segmented-flow platform for 3D cell cultivation. J. Biotechnol. 2015, 205, 59-69.

Meta, A.; Hirashima, M.; Imamura, T.; Kawamura, R.; Yano, K.; Uehara, K.; Nakashima, T. High-yield preparation of recombinant human α-thrombin for therapeutic use. J. Biosci. Bioeng. 2015, 120 (4), 432-437.

GHS Hazard and Precautionary Statements

Hazard Statements: H334-H317

May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.

Precautionary Statements: P284-P261-P280g-P342+P311a-P363-P501a

Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves. If experiencing respiratory symptoms: Call a POISON CENTER/doctor. Wash contaminated clothing before reuse. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Harmonized Tariff Code
2941.90
TSCA
No

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