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22071-15-4 - Ketoprofen - (2-[3-Benzoylphenyl]propionic acid) - J62702 - Alfa Aesar

J62702 Ketoprofen

CAS Number
22071-15-4
Synonyms
(2-[3-Benzoylphenyl]propionic acid)

Size Price ($) Quantity Availability
5g 66.80
25g 224.00
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Ketoprofen

MDL
MFCD00055790
EINECS
244-759-8

Chemical Properties

Formula
C16H14O3
Formula Weight
254.29
Form
Powder
Melting point
92-97°
Solubility
Slightly soluble in chloroform and methanol.

Applications

It is used as a anti-inflammatory; analgesic and an antipyretic drug cause the hypothalamus to override an interleukin-induced increase in temperature. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Osipova NA, T.D, et al. Ketoprofen (ketonal): a drug for preventing and treating postoperative pain.Anesteziologiia i reanimatologiia.,1999,671-74.

Ting ST, et al. Effect of ketoprofen, lidocaine local anesthesia, and combined xylazine and lidocaine caudal epidural anesthesia during castration of beef cattle on stress responses, immunity, growth, and behavior.Journal of animal science.,2003,81(5), 1281-1293.

GHS Hazard and Precautionary Statements

Hazard Statements: H301-H315-H319-H335

Toxic if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P280a-P301+P310a-P305+P351+P338-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF SWALLOWED: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5305
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2918.30
TSCA
Yes
RTECS
UE7570000

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