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38396-39-3 - Bupivacaine - J62742 - Alfa Aesar

J62742 Bupivacaine

CAS Number
38396-39-3
Synonyms

Size Price ($) Quantity Availability
1g 111.20
5g 244.11
25g 727.20
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Bupivacaine

MDL
MFCD00243007
EINECS
253-911-2

Chemical Properties

Formula
C18H28N2O
Formula Weight
288.43
Form
Cyrstalline powder
Melting point
106-110°
Solubility
Soluble in water, ethanol, chloroform (slightly ), and acetone (slightly ).

Applications

Bupivacaine acts as a potent and long-acting local anesthetic agent in vivo. At 100 µM, it has been reported to inhibit the uptake of dopamine in striatal synaptosomes by 47%.

Notes

Store at controlled room temperature of 15-30°C (59-86°F). Protect from freezing and extreme heat.

Literature References

Chahar P & Cummings KC. Liposomal bupivacaine: a review of a new bupivacaine formulation. J Pain Res . 2012, 5, (pt 12), 257-64.

Covino BG Pharmacology of local anaesthetic agents. Br J Anaesth . 1986, 58, (7), 701-16.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H310-H330

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.

Precautionary Statements: P260-P284-P301+P310-P304+P340-P320-P330-P361-P302+P350-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear respiratory protection. IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Remove/Take off immediately all contaminated clothing. IF ON SKIN: Gently wash with plenty of soap and water. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2933.39
TSCA
Yes

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