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Bupivacaine acts as a potent and long-acting local anesthetic agent in vivo. At 100 µM, it has been reported to inhibit the uptake of dopamine in striatal synaptosomes by 47%.
Chahar P & Cummings KC. Liposomal bupivacaine: a review of a new bupivacaine formulation. J Pain Res . 2012, 5, (pt 12), 257-64.
Covino BG Pharmacology of local anaesthetic agents. Br J Anaesth . 1986, 58, (7), 701-16.
Hazard Statements: H300-H310-H330
Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.
Precautionary Statements: P301+P310a-P304+P340-P320-P330-P405-P501a
IF SWALLOWED: IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.