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70288-86-7 - Ivermectin - 22,23-Dihydroavermectin B1 - MK-933 - J62777 - Alfa Aesar

J62777 Ivermectin

CAS Number
70288-86-7
Synonyms
22,23-Dihydroavermectin B1
MK-933

Size Price ($) Quantity Availability
250mg 20.50
1g 64.00
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Ivermectin

MDL
MFCD00869511
EINECS
274-536-0

Chemical Properties

Formula
C48H74O14
Formula Weight
875.11
Form
Powder
Solubility
Soluble in methyl ethyl ketone (50 mg/ml), and DMSO (50 mM).

Applications

It is used as a positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C.

Literature References

H Marti.; HJ Haji.; L Savioli.; HM Chwaya. A comparative trial of a single-dose ivermectin versus three days of albendazole for treatment of Strongyloides stercoralis and other soil-transmitted helminth infections . The American Journal of Tropical Medicine and Hygiene. 1996, 55(5), 477-481.

R Wall.; L Strong. Environmental consequences of treating cattle with the antiparasitic drug ivermectin. Nature. 1987, 327(5), 418 - 421.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H319-H360

Fatal if swallowed. Causes serious eye irritation. May damage fertility or the unborn child.

Precautionary Statements: P201-P280-P301+P310a-P305+P351+P338-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,5248
Hazard Class
6.1
Packing Group
I
Harmonized Tariff Code
2932.20
TSCA
No
RTECS
IH7891500

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