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73360-54-0 - Bupivacaine hydrochloride monohydrate, 98+% - Marcaine - Carbostesin - J62835 - Alfa Aesar

J62835 Bupivacaine hydrochloride monohydrate, 98+%

CAS Number
73360-54-0
Synonyms
Marcaine
Carbostesin

Size Price ($) Quantity Availability
1g 50.90
5g 152.00
25g 646.00
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Bupivacaine hydrochloride monohydrate, 98+%

MDL
MFCD00078956
EINECS
241-917-8

Chemical Properties

Formula
C18H28N2O•HCl•H2O
Formula Weight
342.90
Form
White powder
Melting point
255-259°
Solubility
Soluble in water to 50 mM, in DMSO to 100 mM and in ethanol to 100 mM.

Applications

It is employed as Na+ channel blocker, local anesthetic and cAMP production inhibitor. It acts as a surfactant molecule possessing both hydrophilic and lipophilic properties, adrenergic antagonist, EC 3.1.1.8 (cholinesterase) inhibitor and EC 3.6.3.8 (Ca(2+)-transporting ATPase) inhibitor.

Notes

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Literature References

Viscusi ER, et al. The safety of liposome bupivacaine, a novel local analgesic formulation.Clinical pharmacology and therapeutics.,2014,30(2), 102-110.

Hu D, et al. Pharmacokinetic profile of liposome bupivacaine injection following a single administration at the surgical site.Clinical drug investigation.,2013,33(2), 109-115.

GHS Hazard and Precautionary Statements

Hazard Statements: H300-H310-H330

Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled.

Precautionary Statements: P301+P310a-P304+P340-P320-P330-P405-P501a

IF SWALLOWED: IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Specific treatment is urgent (see label). Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,1495
Hazard Class
6.1
Packing Group
II
Harmonized Tariff Code
2933.39
TSCA
No
RTECS
TK6125000

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