A potent protease inhibitor.Aprotinin acts as a reversible serine protease blocking and a binding agent. It is widely employed as an inhibitor of trypsin. It is also used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones. It is involved in the purification of urokinase, trypsin, and chymotrypsin on immobilized aprotinin. Further, it is used in the quantification of kallikrein activity in mixtures of esterases and proteases.
Xin, Y.; Liu, L.; Chen, B.; Zhang, L.; Tong, Y. Affinity purification of aprotinin from bovine lung. J. Sep. Sci. 2015, 38 (9), 1441-1448.
Brannon, J. R.; Burk, D. L.; Leclerc, J. M.; Thomassin, J. L.; Portt, A.; Berghuis, A. M.; Gruenheid, S.; Moual, H. L. Inhibition of Outer Membrane Proteases of the Omptin Family by Aprotinin. Infect. Immun. 2015, 83 (6), 2300-2311.
Precautionary Statements: P260-P201-P280-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.