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J63060 Spermine tetrahydrochloride, 99%

CAS Number
306-67-2
Synonyms
N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride

Stock No. Size Price ($) Quantity Availability
J63060-03 1g 24.60
J63060-06 5g 98.30
J63060-14 25g 389.00
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Spermine tetrahydrochloride, 99%

MDL
MFCD00012914
EINECS
206-189-8

Chemical Properties

Formula
C10H26N4•4HCl
Formula Weight
348.19
Form
Powder
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble in water (348.2 g/L at 20°C).

Applications

Spermine tetrahydrochloride, is used to precipitate DNA from low salt aqueous buffers. Spermine tetrahydrochloride was used to precipitate DNA for flow cytometric analysis from fresh frozen breast cancer tissue, archival tissue of salivary gland, renal and thyroid tumors2 and red blood cells of chicken.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Hygroscopic. Store under inert gas. Keep away from strong oxidizing agents.

Literature References

Benveniste and Mayer. Multiple effects of spermine on N-methyl-D-aspartic acid receptor responses of rat cultured hippocampal neurones. J.Physiol. 1993, 464, (2), 131-63.

Munir et al. Polyamines modulate the neurotoxic effects of NMDA in vivo. Brain Res. 1993, 616, (1-2), 163-70.

GHS Hazard and Precautionary Statements

Hazard Statements: H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Precautionary Statements: P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P501c

Avoid breathing dust/fume/gas/mist/vapours/spray. Wash face, hands and any exposed skin thoroughly after handling Use only outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Call a POISON CENTER or doctor/physician if you feel unwell. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Beilstein
3911771
Harmonized Tariff Code
2921.29
TSCA
Yes
RTECS
EJ7230000

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