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A useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one.
Devi, T. S. R.; Kumar, J. S.; Ramkumaar, G. R. DFT simulations and vibrational spectra of 2-amino-2-methyl-1,3-propanediol. Spectrochim. Acta, Part A 2014, 133, 214-222.
Mekala, P.; Kamisetty, V.; Chien, W. M.; Shi, R.; Chandra, D.; Sangwai, J.; Talekar, A.; Mishra, A. Thermodynamic modeling of binary phase diagram of 2-amino-2-methyl-1,3-propanediol and TRIS(hydroxymethyl)aminomethane system with experimental verification. Calphad 2015, 50, 126-133.
Hazard Statements: H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statements: P260-P201-P280g-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.