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24169-02-6 - Econazole nitrate - Ecostatin - 1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate - J63173 - Alfa Aesar

J63173 Econazole nitrate

CAS Number
24169-02-6
Synonyms
Ecostatin
1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate

Size Price ($) Quantity Availability
5g 53.80
25g 220.00
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Econazole nitrate

MDL
MFCD00058160
EINECS
246-053-5

Chemical Properties

Formula
C18H15Cl3N2O•HNO3
Formula Weight
444.70
Form
Powder
Melting point
158-163°
Solubility
Soluble at 0.4mg/ml in DMSO. Sparingly soluble in water.

Applications

Econazole nitrate is an antifungal medication often used as a cream to treat skin infections like tinea, ringworm and athlete's foot, personal care, cosmetic and pharmaceutical applications. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes.

Notes

Keep container tightly closed. Store away from oxidizing agents. Store in cool, dry conditions in well sealed containers.

Literature References

Poonam Verma.; Kamla Pathak. Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation. Nanomedicine: Nanotechnology, Biology and Medicine. 2012, 8, (4), 489-496.

Vanna Sanna.; Giuseppe Caria.; Alberto Mariani. Effect of lipid nanoparticles containing fatty alcohols having different chain length on the ex vivo skin permeability of Econazole nitrate. Powder Technology. 2010, 201, (1), 32-36.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P280a-P305+P351+P338-P301+P312a-P321-P332+P313-P501a

Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Specific treatment (see label). If skin irritation occurs: Get medical advice/attention. Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References

Merck
14,3502
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
NI4450000

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