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J63173 Econazole nitrate

CAS Number
24169-02-6
Synonyms
Ecostatin
1-[2-(4-Chlorophenylmethoxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate

Stock No. Size Price ($) Quantity Availability
J63173-06 5g 54.20
J63173-14 25g 247.00
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Econazole nitrate

MDL
MFCD00058160
EINECS
246-053-5

Chemical Properties

Formula
C18H15Cl3N2O•HNO3
Formula Weight
444.70
Form
Powder
Melting point
158-163°
Storage & Sensitivity
Ambient temperatures.
Solubility
Soluble at 0.4mg/ml in DMSO. Sparingly soluble in water.

Applications

Econazole nitrate is an antifungal medication often used as a cream to treat skin infections like tinea, ringworm and athlete's foot, personal care, cosmetic and pharmaceutical applications. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes.

Notes

Keep container tightly closed. Store away from oxidizing agents. Store in cool, dry conditions in well sealed containers.

Literature References

Poonam Verma.; Kamla Pathak. Nanosized ethanolic vesicles loaded with econazole nitrate for the treatment of deep fungal infections through topical gel formulation. Nanomedicine: Nanotechnology, Biology and Medicine. 2012, 8, (4), 489-496.

Vanna Sanna.; Giuseppe Caria.; Alberto Mariani. Effect of lipid nanoparticles containing fatty alcohols having different chain length on the ex vivo skin permeability of Econazole nitrate. Powder Technology. 2010, 201, (1), 32-36.

GHS Hazard and Precautionary Statements

Hazard Statements: H302-H315-H319

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Precautionary Statements: P264b-P270-P280-P301+P312-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362-P501c

Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF ON SKIN: Wash with plenty of soap and water. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Rinse mouth. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Take off contaminated clothing and wash before reuse. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,3502
Harmonized Tariff Code
2933.29
TSCA
No
RTECS
NI4450000

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