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J63190 Ebselen

CAS Number
60940-34-3
Synonyms

Stock No. Size Price ($) Quantity Availability
J63190-MA 10mg 67.20
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Ebselen

MDL
MFCD00210937

Chemical Properties

Formula
C13H9NOSe
Formula Weight
274.20
Form
Powder
Melting point
180-181°
Storage & Sensitivity
Store at -20°C.
Solubility
Soluble in ethanol, methanol, acetone, acetonitrile.

Applications

Ebselen inhibits 5-LO, CO, NADPH oxidize, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.

Notes

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Literature References

Helmut Sies. Ebselen, a selenoorganic compound as glutathione peroxidase mimic. Free Radical Biology and Medicine. 1993, 14,(3), 313-323.

Tankred Schewe. Molecular actions of Ebselen—an anti-inflammatory antioxidant. General Pharmacology: The Vascular System. 1995, 26,(6), 1153-1169.

GHS Hazard and Precautionary Statements

Hazard Statements: H330-H373

Fatal if inhaled. May cause damage to organs through prolonged or repeated exposure.

Precautionary Statements: P260-P271-P284-P304+P340-P310-P314-P501c

Do not breathe dust/fume/gas/mist/vapours/spray. Use only outdoors or in a well-ventilated area. Wear respiratory protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Get medical advice/attention if you feel unwell. Dispose of contents/ container to an approved waste disposal plant

Other References

Merck
14,3486
Hazard Class
6.1
Packing Group
III
Harmonized Tariff Code
2934.99
TSCA
No
RTECS
DE4140750

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